Tag: Diagnostics

Echo? Who, what, when, how? Role of echo modality in Staph aureus bacteremia.

I absolutely love this song. I tried to learn how to play it on guitar, but I think you may need 7 strings for it, at least when I checked back in the day. This week we are adding to last week’s topic and talking about when and what type of echo to get. There

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Infective Endocarditis: A Journey Through Definitions

At any rate, at approximately one-quarter to twelve that night, I remember distinctly getting up from my chair and from the table, where my books lay, and taking off my suit coat. No sooner had I removed the left arm of my coat, than there was on the ventral aspect of my left wrist a

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Query: A Journey from Ruminants to Heart Valves

Last post was all about dogs and their mouths. This time, is about cow placentas. At least to a certain extent. Coxiella burnetii is a gram negative organism that is known to cause a variety of diseases, however it is most commonly associated with culture-negative endocarditis. While it is generally a “wimpy” organism and not

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Role of Rigors in Bacteremia – Do Not Ignore Chills

Blood cultures are typically drawn in patients who present with sepsis due to concern for infection. While the trigger response to “fevers and leukocytosis” is to obtain blood cultures, the positive rate that has been quoted ranges from 4-7% (1), depending on the source. Indeed, blood culture contamination is a frequent problem that is encountered

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Diagnostic Tools for Pulmonary Tuberculosis

Pulmonary tuberculosis is a global disease that tends to burden underdeveloped countries disproportionally as well people living with HIV. It is a difficult disease to diagnose in the microbiology lab, and as such, there have been various methods deployed in an attempt to diagnose it. While culture is the gold standard, it can take anywhere

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Procalcitonin in Infectious Disease

Procalcitonin is a precursor of the hormone calcitonin and is released into systemic circulation within 4 hours of inoculation of bacterial endotoxin, In general, cytokines enhance procalcitonin release while interferons, which are released in context of viral infections. Because of this, there has been a push towards using PCT to differentiate bacterial from viral infections

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The Diagnosis of the French Disease in the Year 2020

The spread of syphilis in 1494/1495 in Italy is the first known instance of an outbreak of the disease. It is believed the disease was brought in from the New World by Columbus and his crew members and following the invasion of France in Naples, Italy, the disease began to spread throughout Europe. Known as

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The Role of Physical Exam in Pneumonia – An Oslerian Relic or a Modern Hidden Gem?

I am probably not the only one who doubts the utility of the physical exam in the diagnosis of disease. Indeed, when looking at the imaging modalities that we have at hand, including CT, MRI, PET, Echo, ultrasound, and how quickly we can get any of these studies now, the physical exam seems to be

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