Month: April 2021

Basics of Yellow Fever – i.e The Bare Minimum

Flaviviruses flabber my gaster. There are multiple of these that all look the same and all cause very similar diseases (read: hemorrhagic fever). Dengue, West Nile, and Zika are the more widely known given the recent outbreaks in the US of the latter 2. The one that is of historical (and epidemiological) importance is yellow

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The Shapiro Score, or How “Facts Don’t Care About Blood Cultures.”

Does anyone remember signing out as residents, how there is always a line that goes something along the lines of “if fever, then culture.” As in fever always means there is an infection, or at least a suspicion of it. Of course, fever means inflammation but infection is a type of inflammation so why not

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The Trouble with MDR and XDR-TB – New Drugs Needed

Pulmonary tuberculosis is one of those infections that is difficult enough to treat under the best circumstances, as it requires the patient to take four drugs for an extended period of time. The development of resistance to any of the core drugs complicates matters, as it forces physicians to use other types of medications that

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Weekly Articles: 3/28/2021

Janiaud P, Axfors C, Schmitt AM, et al. Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19: A Systematic Review and Meta-analysis. JAMA. 2021;325(12):1185–1195. doi:10.1001/jama.2021.2747 This is a meta-analysis consisting of all RCTs published in peer-reviewed journals as well as pre-prints evaluating convalescent plasma in confirmed or suspected COVID patients. Primary outcomes

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