Category: Tuberculosis

Interferon Gamma Release Assays: How Do They Work?

Unfortunately, i have not being able to figure out how to rotate some of the images on WordPress, despite my google docs being in the correct configuration. Hence, some tables are rotated the wrong way. Do know I tried to fix it. I have been putting off writing about this since the immunology behind this

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TB or not TB: A Journey Through Chemotherapy

This is quite a corny and overtold joke. I have discussed some new drugs for multidrug resistant tuberculosis (MDR-TB), which is defined as resistance to both rifampin and isoniazid, however I felt like going back to the basics of TB therapy. Indeed, we all learn in STEP 1 and med school about “RIPE-ing it up”

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The Trouble with MDR and XDR-TB – New Drugs Needed

Pulmonary tuberculosis is one of those infections that is difficult enough to treat under the best circumstances, as it requires the patient to take four drugs for an extended period of time. The development of resistance to any of the core drugs complicates matters, as it forces physicians to use other types of medications that

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Tuberculous Meningitis – What You Need to Know

I think I have talked quite a bit about tuberculosis these past few posts. This is because it is difficult to diagnose in certain cases, it can infect virtually any organ, and it can become deadly once it infects any other organ outside of the lungs. Namely the CNS. Tuberculous meningitis is a deadly disease,

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Pericardial Tuberculosis – A Nightmare in Diagnosis

Diagnosing pulmonary tuberculosis can be a tricky thing. As highlighted previously, the Ziehl-Neelsen smear is not a terribly sensitive methodology and the MTB-PCR sensitivity depends on if the sample is smear positive. Given that pulmonary tuberculosis tends to have a higher bacterial burden, it would be reasonable to think that other diseases without this high

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Diagnostic Tools for Pulmonary Tuberculosis

Pulmonary tuberculosis is a global disease that tends to burden underdeveloped countries disproportionally as well people living with HIV. It is a difficult disease to diagnose in the microbiology lab, and as such, there have been various methods deployed in an attempt to diagnose it. While culture is the gold standard, it can take anywhere

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