Galactomannan is a component of the cell wall of both Aspergillus spp and Penicillium spp. This component is secreted during the growth phase of the fungus, and higher galactomannan levels are correlated with fungal load in tissues. This is the general structure of the galactomannan: The test of choice is a sandwich ELISA. The double-sandwich
Tag: Diagnostics
Lyme disease is a difficult beast to diagnose. I think most people know some of the characteristics, including the fact it is a vector-borne illness that causes a characteristic rash (EM) that can lead to CNS disease, cardiac disease, and large joint arthritis. While the clinical characteristics are known, there is some difficulty in diagnosing
This is the cell wall of fungi. It is not inert and, the cell wall undergoes a consistent process of assembly and remodeling during cell growth. Glucan is the most abundant polysaccharide, and it is made up of glucose polymers linked by carbon at the first and third position: Back in the day (roughly the