Tag: Aspergillus

Influenza, COVID-19, Pulmonary Aspergillosis, Lions, Tigers, And Bears – Oh My!

Influenza season is right around the corner, and given the current circumstances, it is a terrifying thought to have both COVID and flu running around. Besides causing significant respiratory distress and subsequent ARDS, severe influenza leads to bacterial superinfection with organisms such as Staph aureus and Streptococcal pneumonia. This usually happens in 10-35% of cases

Continue reading

The Secret of Galactomannan – Utility in IPA

Galactomannan is a component of the cell wall of both Aspergillus spp and Penicillium spp. This component is secreted during the growth phase of the fungus, and higher galactomannan levels are correlated with fungal load in tissues. This is the general structure of the galactomannan: The test of choice is a sandwich ELISA. The double-sandwich

Continue reading

Halo Sign for Pulmonary Aspergillosis – Not as Great as You Once Thought.

The timely diagnosis of invasive pulmonary aspergillosis is incredibly important. Non-invasive modalities of diagnosis such as beta-D glucan and galactomannan can take a few days to come back and much of the time, we rely on chest imaging to guide treatment decision. The classic finding that has been attributed to invasive pulmonary aspergillosis has been

Continue reading