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What is this? I am writing about a topic related to transplant infectious diseases? Something has to be going on! I had originally intended to write about CMV serostatus and risk of organ rejection in SOT patients, but that was a more difficult topic to tackle (just like that HTLV-1 post; yeah that one is
Liao X, Wang Y, He Z, et al. Three-month pulmonary function and radiological outcomes in COVID-19 survivors: a longitudinal patient cohort study. Open Forum Infect Dis. 2020;ofaa540. Published 2020 Nov 14. doi:10.1093/ofid/ofaa540 How does pulmonary function fare following COVID infection? This retrospective study 172 patients who were hospitalized with COVID and evaluated both CT and
Primary infection with T. cruzi, also known as American trypanosomiasis, is generally asymptomatic with a small percentage having non-specific symptoms such as fever, malaise, lymphadenopathy, and in certain cases, a Chagoma. The vast majority of people go on to develop an “intermediate” form of the disease, where serology is positive but there is no sign
ATTACC Investigators; ACTIV-4a Investigators; REMAP-CAP Investigators, Lawler PR, Goligher EC, Berger JS, et al. Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19. N Engl J Med. 2021 Aug 26;385(9):790-802. doi: 10.1056/NEJMoa2105911. Epub 2021 Aug 4. PMID: 34351721; PMCID: PMC8362594. A pair of articles on anticoagulation. The first one is on non-critically ill patients
This is going to be a very different post, in that, while the topic is still related to infectious disease, I’ll delve into other parts of medicine as I think they are relevant. Chagas disease, widely considered a neglected tropical disease, is caused by Trypanosoma cruzi and it is a zoonosis transmitted among domestic and
Lopez Bernal J, Andrews N, Gower C, Gallagher E, Simmons R, Thelwall S, Stowe J, Tessier E, Groves N, Dabrera G, Myers R, Campbell CNJ, Amirthalingam G, Edmunds M, Zambon M, Brown KE, Hopkins S, Chand M, Ramsay M. Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant. N Engl J Med. 2021 Aug 12;385(7):585-594.
Last post was all about dogs and their mouths. This time, is about cow placentas. At least to a certain extent. Coxiella burnetii is a gram negative organism that is known to cause a variety of diseases, however it is most commonly associated with culture-negative endocarditis. While it is generally a “wimpy” organism and not
Not as many articles this week to go over, but nevertheless some interesting ones. REMAP-CAP Investigators; ACTIV-4a Investigators; ATTACC Investigators. Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19. N Engl J Med. 2021 Aug 4. doi: 10.1056/NEJMoa2103417. Epub ahead of print. PMID: 34351722. More on anticoagulation and COVID. This was an international, multiplatform,
There are multiple associations in medicine where the mere mention of a location, occupation, or risk factor elicits a response with regards to the disease. In infectious disease, there are multiple such as “spelunking” being associated with histoplasmosis, IV drug abuser associated with MRSA endocarditis, or cows placentas being associated with Q fever. When it
Tons on COVID and a few interesting HIV articles. Vafa Bayat, Russell Ryono, Steven Phelps, Eugene Geis, Farshid Sedghi, Payam Etminani, Mark Holodniy, Reduced Mortality With Ondansetron Use in SARS-CoV-2-Infected Inpatients, Open Forum Infectious Diseases, Volume 8, Issue 7, July 2021, ofab336, https://doi.org/10.1093/ofid/ofab336 Does zofran help with COVID-19 mortality? Maybe. This was a retrospective cohort
Dr. Germophile 