What to start?
In general, start any combination that has an integrase inhibitor. In general, either
- Descovy OR Truvada + Dolutegravir
- Biktarvy (I think the most popular choice)
- Triumeq (if no HLA-B5701)
There are newer combinations, which I will not go over (for instance, Dovato aka 3TC/DTG, Juluca aka DTG/RPV, Delstrigo aka TDF/3TC/DOR) nor will I go over entry inhibitors since they are not typically seen in practice.
Also note that protease inhibitors tend to react with everything under the sun, so watch for drug-drug interactions when using these.