HIV Main Meds – Cheat Sheet

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What to start?

In general, start any combination that has an integrase inhibitor. In general, either

  • Descovy OR Truvada + Dolutegravir
  • Biktarvy (I think the most popular choice)
  • Triumeq (if no HLA-B5701)

There are newer combinations, which I will not go over (for instance, Dovato aka 3TC/DTG, Juluca aka DTG/RPV, Delstrigo aka TDF/3TC/DOR) nor will I go over entry inhibitors since they are not typically seen in practice.

Also note that protease inhibitors tend to react with everything under the sun, so watch for drug-drug interactions when using these.

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