Tag: Zosyn

ESBL Infections: A Conundrum Yet to be Figured Out

Extended spectrum-beta lactamase producing organisms are those gram negatives that make beta-lactamases that inhibit third and fourth generation cephalosporins. As such, things such as piperacillin-tazobactam tends to show up as susceptible in antibiograms, however there has been a push lately towards the use of carbapenems as therapy for infections with these organisms. It seems kind

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The Nephrotoxicity of Piperacillin-Tazobactam

Depending on where you practice, I think it is safe to assume there is a “nickname” for the combination of vancomycin/piperacillin-tazobactam (VAN/PTZ). “Guerilla-cillin,” “Parkla-mycin” or just “the big guns” this is a very common combination that is thrown up front for sepsis or health-care acquired infections (the debate of whether this is an appropriate approach

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