Tag: Amphotericin B

Iatrogenic Fungal Meningitis – We’re Here Again

Meningitis is defined as inflammation of the meninges, characterized by an abnormal number of WBCs on the CSF. The most common cause of meningitis is viral, with organisms such as echovirus, coxsackievirus, and the enteroviruses being a common etiology. Further, bacterial meningitis can be caused by H. influenzae and Streptococcus spp. One odd etiology is

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Antifungals for Candida Infective Endocarditis – Where is the Data?

Candida and staphylococcus are two fairly common isolates of bloodstream infections, as well as part of our own microbiome. These two organisms also instill the fear of God into me, given how sticky they can be. I’ve talked a lot about staphylococcus and endocarditis in general, so candida endocarditis gets the spotlight for this post.

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Cryptococcus Meningitis – Making Amphotericin Float Like a Crashing Seagull and Sting Like a Scorpion

Am I going there? Am I going to look into a topic that one of my attendings literally wrote the guidelines for? I guess I am. Cryptococcus is a yeast that is typically found everywhere there is bat/pigeon droppings or contaminated soil, as well as in certain tree species throughout the world. The most common

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Types of Amphotericin B – What I Didn’t Know

I’ve been reading quite a bit about antifungals lately and one of the things I realized is the many formulations of amphotericin. Actually, the realization I had was I didn’t know the differences between them. It is a polyene antifungal that has broad spectrum antifungal activity (including Leshmania spp) but it is limited by its

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