Candida and staphylococcus are two fairly common isolates of bloodstream infections, as well as part of our own microbiome. These two organisms also instill the fear of God into me, given how sticky they can be. I’ve talked a lot about staphylococcus and endocarditis in general, so candida endocarditis gets the spotlight for this post.
Echinocandins. This is the drug we use mostly on the inpatient side for invasive candidiasis. The most well known is micafungin, but analdafungin is another option that is also commonly used. Besides resistance, the issue with echinocandins are the fact they are intravenous drugs, which makes administration of it easy on the inpatient side but