Where all your ID needs are met! Sort of.
This is going to be a very different post, in that, while the topic is still related to infectious disease, I’ll delve into other parts of medicine as I think they are relevant. Chagas disease, widely considered a neglected tropical disease, is caused by Trypanosoma cruzi and it is a zoonosis transmitted among domestic and
Lopez Bernal J, Andrews N, Gower C, Gallagher E, Simmons R, Thelwall S, Stowe J, Tessier E, Groves N, Dabrera G, Myers R, Campbell CNJ, Amirthalingam G, Edmunds M, Zambon M, Brown KE, Hopkins S, Chand M, Ramsay M. Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant. N Engl J Med. 2021 Aug 12;385(7):585-594.
Last post was all about dogs and their mouths. This time, is about cow placentas. At least to a certain extent. Coxiella burnetii is a gram negative organism that is known to cause a variety of diseases, however it is most commonly associated with culture-negative endocarditis. While it is generally a “wimpy” organism and not
Not as many articles this week to go over, but nevertheless some interesting ones. REMAP-CAP Investigators; ACTIV-4a Investigators; ATTACC Investigators. Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19. N Engl J Med. 2021 Aug 4. doi: 10.1056/NEJMoa2103417. Epub ahead of print. PMID: 34351722. More on anticoagulation and COVID. This was an international, multiplatform,
There are multiple associations in medicine where the mere mention of a location, occupation, or risk factor elicits a response with regards to the disease. In infectious disease, there are multiple such as “spelunking” being associated with histoplasmosis, IV drug abuser associated with MRSA endocarditis, or cows placentas being associated with Q fever. When it
Tons on COVID and a few interesting HIV articles. Vafa Bayat, Russell Ryono, Steven Phelps, Eugene Geis, Farshid Sedghi, Payam Etminani, Mark Holodniy, Reduced Mortality With Ondansetron Use in SARS-CoV-2-Infected Inpatients, Open Forum Infectious Diseases, Volume 8, Issue 7, July 2021, ofab336, https://doi.org/10.1093/ofid/ofab336 Does zofran help with COVID-19 mortality? Maybe. This was a retrospective cohort
I discussed C. auris in my last post and pointed out that, due to the relative novelty of the organism, there are no “defined” breakpoints when it comes to drug-bug combinations. While I did say that fluconazole, in many instances, was considered “resistant”, the truth is I cannot say that with 100% confidence as there
Ear yeast! That is the translation of Candida auris. It was discovered by isolation from an ear infection in an elderly patient in Japan in 2009 and since then it has been isolated in places such as India, southeast Asia and several parts of south America (1-4): One of the defining characteristics is its resistance
The use of rifampin for staphylococcal infections is a bit controversial. The recommendation seems to be its use on infections involving prosthetic material, such as prosthetic valve endocarditis or prosthetic joint infections. For instance, the AHA infective endocarditis (1) guidelines recommends the addition of rifampin to a regimen consisting of vancomycin to infectious caused by
Zachary A Yetmar, Supavit Chesdachai, Tarek Kashour, Muhammad Riaz, Danielle J Gerberi, Andrew D Badley, Elie F Berbari, Imad M Tleyjeh, Prior Statin Use and Risk of Mortality and Severe Disease From Coronavirus Disease 2019: A Systematic Review and Meta-analysis, Open Forum Infectious Diseases, Volume 8, Issue 7, July 2021, ofab284, https://doi.org/10.1093/ofid/ofab284 This was a
Dr. Germophile 