Allen, John M., et al. “Cefazolin Versus Anti-Staphylococcal Penicillins for the Treatment of Patients With Methicillin-Susceptible Staphylococcus Aureus Infection: a Meta-Analysis With Trial Sequential Analysis.” Infectious Diseases and Therapy, vol. 8, no. 4, 2019, pp. 671-686.
This one is not groundbreaking but nice to have data supporting our decisions. This was a review of the literature evaluating the efficacy of cefazolin vs anti-staphylococcal penicillin (cloxacillin, nafcillin, flucoxacillin) in staph aureus bacteremia. The primary end point was 90d all cause mortality; secondary end point was 30d all cause mortality, treatment failure/relapse, and