A bit late on this one but I have some info on the delta variant. Lustig Y, Zuckerman N, Nemet I, Atari N, Kliker L, Regev-Yochay G, Sapir E, Mor O, Alroy-Preis S, Mendelson E, Mandelboim M. Neutralising capacity against Delta (B.1.617.2) and other variants of concern following Comirnaty (BNT162b2, BioNTech/Pfizer) vaccination in health care
Category: Article Summaries
Surial B, Mugglin C, Calmy A, Cavassini M, Günthard HF, Stöckle M, Bernasconi E, Schmid P, Tarr PE, Furrer H, Ledergerber B, Wandeler G, Rauch A; Swiss HIV Cohort Study. Weight and Metabolic Changes After Switching From Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in People Living With HIV : A Cohort Study. Ann Intern Med.
Some isavuconazole news, a PJI trial, a few HIV-related articles, and therapies for COVID that won’t die. Maertens JA, Raad II, Marr KA, Patterson TF, Kontoyiannis DP, Cornely OA, Bow EJ, Rahav G, Neofytos D, Aoun M, Baddley JW, Giladi M, Heinz WJ, Herbrecht R, Hope W, Karthaus M, Lee DG, Lortholary O, Morrison VA,
Quite a few here. A brief word on the new vancomycin dosing guidelines, dual therapy for enterococcal IE and MRSA bacteremia, and several updates on COVID-19. Anna Poston-Blahnik, Ryan Moenster, Association Between Vancomycin Area Under the Curve and Nephrotoxicity: a single center, retrospective cohort study in a veteran population, Open Forum Infectious Diseases, Volume 8,
Some interesting articles this time around. This is a pair of articles that came out in the recent Lancet ID issue and deals with the use of antiseptic mouthwash and its role in preventing STIs. Chow EPF, Williamson DA, Hocking JS, Law MG, Maddaford K, Bradshaw CS, McNulty A, Templeton DJ, Moore R, Murray GL,
COVID vaccine news, shorter antibiotics for pneumonia, and odd bugs in odd places. Kortela E, Kanerva MJ, Puustinen J, Hurme S, Airas L, Lauhio A, Hohenthal U, Jalava-Karvinen P, Nieminen T, Finnilä T, Häggblom T, Pietikäinen A, Koivisto M, Vilhonen J, Marttila-Vaara M, Hytönen J, Oksi J. Oral Doxycycline Compared to Intravenous Ceftriaxone in the
Disappointing HIV vaccine news, more MDR TB, and a possible HITting complication for one of the new COVID vaccines. Gray GE, Bekker LG, Laher F, Malahleha M, Allen M, Moodie Z, Grunenberg N, Huang Y, Grove D, Prigmore B, Kee JJ, Benkeser D, Hural J, Innes C, Lazarus E, Meintjes G, Naicker N, Kalonji D,
Janiaud P, Axfors C, Schmitt AM, et al. Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19: A Systematic Review and Meta-analysis. JAMA. 2021;325(12):1185–1195. doi:10.1001/jama.2021.2747 This is a meta-analysis consisting of all RCTs published in peer-reviewed journals as well as pre-prints evaluating convalescent plasma in confirmed or suspected COVID patients. Primary outcomes
Richard G Wunderink, Antoine Roquilly, Martin Croce, Daniel Rodriguez Gonzalez, Satoshi Fujimi, Joan R Butterton, Natasha Broyde, Myra W Popejoy, Jason Y Kim, Carisa De Anda, A Phase 3, Randomized, Double-Blind Study Comparing Tedizolid Phosphate and Linezolid for Treatment of Ventilated Gram-Positive Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia, Clinical Infectious Diseases, 2021;, ciab032, https://doi.org/10.1093/cid/ciab032 This is
Huzzah! I have been meandering this week in terms of my writing (work + I can get lazy sometimes). Some new topics coming in the future (including: hyperviscous Klebsiella, hemorrhagic fevers, and post-Chikungunya arthritis), whenever I get to them. But for now, just some literature to get through. This pair of articles are a bit
Dr. Germophile 